One-pot Synthesis of Polysubstituted Dihydro-2oxypyrroles Catalyzed by Vanadium (V) oxide
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Abstract:
A mild and efficient synthesis of polysubstituted dihydro-2-oxypyrroles has been developed for the one-pot, four-component domino condensation of dialkyl acetylenedicarboxylate, formaldehyde and aromatic amines using Vanadium (V) oxide as the catalyst at ambient temperature. The use of Vanadium (V) oxide makes this process simple, more convenient, and environmentally friendly.
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Journal title
volume 11 issue 1
pages 115- 123
publication date 2017-01-01
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